Given the date, I would suppose this is the first cartoon in The New Yorker that made reference to the stock market crash of October, 1929. Would be interesting to know if it was drawn before the event.
Leonard Dove in The New Yorker, November 2, 1929
The History Channel aired a fascinating hour on the origins of the Stock Market in NYC a few nights back. Wall Street got its name because there used to be a huge wall there to barricade against another property. It came down, but the name stuck. The original bartering took place outside in the street, no public stocks!